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1

Quantitative Structure-Activity Relationships of Streptococcus pneumoniae MurD Transition State Analogue Inhibitors

Miha Kotnik, Marko Oblak, Jan Humljan, Stanislav Gobec, Uros Urleb, Tom Solmajer

Journal:

Molecular Informatics

Year:

2004

Language:

english

File:

PDF, 278 KB

english, 2004

2

Synthesis and activity of phosphono desmuramyldipeptide analogs

Uroš Urleb, Stanislav Gobec, Dušan Prelog

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1995

Language:

english

File:

PDF, 312 KB

english, 1995

3

Synthesis of new phosphonamidate and phosphinamide desmuramyldipeptide analogs

Stanislav Gobec, Uroš Urleb

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1998

Language:

english

File:

PDF, 355 KB

english, 1998

4

Design, synthesis and biological evaluation of novel desmuramyldipeptide analogs

Žiga Jakopin, Emanuela Corsini, Martina Gobec, Irena Mlinarič-Raščan, Marija Sollner Dolenc

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 721 KB

english, 2011

5

Cinnamic acids as new inhibitors of 17β-hydroxysteroid dehydrogenase type 5 (AKR1C3)

Petra Brožič, Barbara Golob, Nataša Gomboc, Tea Lanišnik Rižner, Stanislav Gobec

Journal:

Molecular and Cellular Endocrinology

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

6

New enzymatic assay for the AKR1C enzymes

Beranič, Nataša, Štefane, Bogdan, Brus, Boris, Gobec, Stanislav, Rižner, Tea Lanišnik

Journal:

Chemico-Biological Interactions

Year:

2013

Language:

english

File:

PDF, 579 KB

english, 2013

7

Endocrine Disruptome—An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding

Kolšek, Katra, Mavri, Janez, Sollner Dolenc, Marija, Gobec, Stanislav, Turk, Samo

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 2.05 MB

english, 2014

8

Six-Membered Hetarenes with Two Identical Heteroatoms || Purines

Yamamoto, Y., Matsumoto, M., Sakya, S. M., Yang, J., Sato, R., Yoshimoto, F. K., Li, Q., Kosarev, S. A., Hagen, T. J., Haider, N., Holzer, W., Zhang, J., von Angerer, S., Kikelj, D., Sato, N., Gobec,

Year:

2004

Language:

english

File:

PDF, 2.56 MB

english, 2004

9

Six-Membered Hetarenes with Two Identical Heteroatoms || Pteridines and Related Structures

Yamamoto, Y., Matsumoto, M., Sakya, S. M., Yang, J., Sato, R., Yoshimoto, F. K., Li, Q., Kosarev, S. A., Hagen, T. J., Haider, N., Holzer, W., Zhang, J., von Angerer, S., Kikelj, D., Sato, N., Gobec,

Year:

2004

Language:

english

File:

PDF, 951 KB

english, 2004

10

Discovery of new MurA inhibitors using induced-fit simulation and docking

Rožman, Kaja, Lešnik, Samo, Brus, Boris, Hrast, Martina, Sova, Matej, Patin, Delphine, Barreteau, Hélène, Konc, Janez, Janežič, Dušanka, Gobec, Stanislav

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

11

Antibacterial and β-Lactamase Inhibitory Activity of Monocyclic β-Lactams

Decuyper, Lena, Jukič, Marko, Sosič, Izidor, Žula, Aleš, D'hooghe, Matthias, Gobec, Stanislav

Journal:

Medicinal Research Reviews

Year:

2017

Language:

english

File:

PDF, 4.63 MB

english, 2017

12

Cathepsin B inhibitors: Further exploration of the nitroxoline core

Sosič, Izidor, Mitrović, Ana, Ćurić, Hrvoje, Knez, Damijan, Brodnik Žugelj, Helena, Štefane, Bogdan, Kos, Janko, Gobec, Stanislav

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 1.83 MB

english, 2018

13

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

Knez, Damijan, Coquelle, Nicolas, Pišlar, Anja, Žakelj, Simon, Jukič, Marko, Sova, Matej, Mravljak, Janez, Nachon, Florian, Brazzolotto, Xavier, Kos, Janko, Colletier, Jacques-Philippe, Gobec, Stanisl

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.68 MB

english, 2018

14

Synthesis and NMR spectroscopic assignment of chlorinated benzimidazole-2-thione derivatives

Proj, Matic, Sosič, Izidor, Gobec, Stanislav

Journal:

Tetrahedron Letters

Year:

2019

Language:

english

File:

PDF, 979 KB

english, 2019

15

Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome

RoÅ¾man, Kaja, Alexander, Evan M., Ogorevc, Eva, BozoviÄar, KriÅ¡tof, SosiÄ, Izidor, Aldrich, Courtney C., Gobec, Stanislav

Journal:

Year:

2020

Language:

english

File:

PDF, 6.28 MB

english, 2020

16

Size Exclusion Chromatography as a Method for Routine Check-Up and Quality Control of Industrial Thermoplastic Polyurethane Systems – Correlation between Molecular Weight and Mechanical and Thermal Properties

Nicolai Aust, Georg Gobec

Journal:

Macromolecular Materials and Engineering

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

17

Gelpermeationschromatographie und Kalibrierung an resolischen Phenol-Formaldehyd-Kondensaten

Georg Gobec, Manfred Dunky, Thomas Zich, Klaus Lederer

Journal:

Macromolecular Materials and Engineering

Year:

1997

File:

PDF, 414 KB

1997

18

Phosphinate Inhibitors of UDP-N-Acetylmuramoyl-L-Alanyl-D-Glutamate: L-Lysine Ligase (MurE)

Katja Štrancar, Audrey Boniface, Didier Blanot, Stanislav Gobec

Journal:

Archiv der Pharmazie

Year:

2007

Language:

english

File:

PDF, 834 KB

english, 2007

19

ChemInform Abstract: Synthesis and Biochemical Evaluation of Some Novel N-Acyl Phosphono- and Phosphinoalanine Derivatives as Potential Inhibitors of the D-Glutamic Acid-Adding Enzyme.

S. Gobec, U. Urleb, G. Auger, D. Blanot

Journal:

Year:

2001

File:

PDF, 30 KB

2001

20

ChemInform Abstract: Synthesis and Modulation of Cytokine Production by Two New Adamantane Substituted Acyclic Desmuramyldipeptide Analogues.

S. Gobec, U. Urleb, S. Simcic, B. Wraber

Journal:

Year:

2001

File:

PDF, 27 KB

2001

21

ChemInform Abstract: A General Synthesis of Ethyl 4-Aminophenyl and Ethyl 4-[Amino(hydroxyimino)methyl]phenyl Phosphonates.

Stanislav Gobec, Katja Strancar, Uros Urleb

Journal:

Year:

2002

File:

PDF, 31 KB

2002

22

A One-Pot Conversion of α-Aminoalkylphosphonous Acids into Monomethyl α-Aminoalkylphosphonates.

Katja Strancar, Stanislav Gobec

Journal:

Year:

2004

File:

PDF, 75 KB

2004

23

Cinnamic Acid Esters as Potent Inhibitors of Fungal 17β-Hydroxysteroid Dehydrogenase — A Model Enzyme of the Short-Chain Dehydrogenase/Reductase Superfamily

Stanislav Gobec, Matej Sova, Katja Kristan, Tea Lanisnik Rizner

Journal:

Year:

2004

File:

PDF, 14 KB

2004

24

Quinoxalines

S. Gobec, U. Urleb

Journal:

Year:

2005

File:

PDF, 8 KB

2005

25

Phenazines

U. Urleb, S. Gobec

Journal:

Year:

2005

File:

PDF, 14 KB

2005

26

ChemInform Abstract: New Cyclopentane Derivatives as Inhibitors of Steroid Metabolizing Enzymes AKR1C1 and AKR1C3.

Bogdan Stefane, Petra Brozic, Matej Vehovc, Tea Lanisnik Rizner, Stanislav Gobec

Journal:

Year:

2009

File:

PDF, 14 KB

2009

27

ChemInform Abstract: The Synthesis of Novel 2,4,6-Trisubstituted 1,3,5-Triazines: A Search for Potential MurF Enzyme Inhibitors.

Izidor Sosic, Bogdan Stefane, Andreja Kovac, Samo Turk, Didier Blanot, Stanislav Gobec

Journal:

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

28

Synthesis and Biological Evaluation of N-Acylhydrazones as Inhibitors of MurC and MurD Ligases

Roman Šink, Andreja Kovač, Tihomir Tomašić, Veronika Rupnik, Audrey Boniface, Julieanne Bostock, Ian Chopra, Didier Blanot, Lucija Peterlin Mašič, Stanislav Gobec, Anamarija Zega

Journal:

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

29

5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases

Tihomir Tomašić, Nace Zidar, Andreja Kovač, Samo Turk, Mihael Simčič, Didier Blanot, Manica Müller-Premru, Metka Filipič, Simona Golič Grdadolnik, Anamarija Zega, Marko Anderluh, Stanislav Gobec, Dani

Journal:

Year:

2010

Language:

english

File:

PDF, 382 KB

english, 2010

30

Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds

Dr. Bojana Mirković, Dr. Miha Renko, Dr. Samo Turk, Izidor Sosič, Dr. Zala Jevnikar, Dr. Nataša Obermajer, Prof. Dr. Dušan Turk, Prof. Dr. Stanislav Gobec, Prof. Dr. Janko Kos

Journal:

Year:

2011

Language:

english

File:

PDF, 550 KB

english, 2011

31

Phosphorylated hydroxyethylamines as novel inhibitors of the bacterial cell wall biosynthesis enzymes MurC to MurF

Matej Sova, Andreja Kovač, Samo Turk, Martina Hrast, Didier Blanot, Stanislav Gobec

Journal:

Bioorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 562 KB

english, 2009

32

Flavonoids and cinnamic acid esters as inhibitors of fungal 17β-hydroxysteroid dehydrogenase: A synthesis, QSAR and modelling study

Matej Sova, Andrej Perdih, Miha Kotnik, Katja Kristan, Tea Lanišnik Rižner, Tom Solmajer, Stanislav Gobec

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 651 KB

english, 2006

33

Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: Synthesis of artificial substrate, homology modelling and initial screening

Mojca Brunskole, Bogdan Štefane, Karmen Zorko, Marko Anderluh, Jure Stojan, Tea Lanišnik Rižner, Stanislav Gobec

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1004 KB

english, 2008

34

Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall

Stanislav Gobec, Ivan Plantan, Janez Mravljak, Rosalind A. Wilson, Gurdyal S. Besra, Danijel Kikelj

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 278 KB

english, 2004

35

Design, synthesis and structure–activity relationships of new phosphinate inhibitors of MurD

Katja Štrancar, Didier Blanot, Stanislav Gobec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

36

Diazenedicarboxamides as inhibitors of d-alanine-d-alanine ligase (Ddl)

Andreja Kovač, Vita Majce, Roman Lenaršič, Sergeja Bombek, Julieanne M. Bostock, Ian Chopra, Slovenko Polanc, Stanislav Gobec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

37

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase

Tihomir Tomašić, Nace Zidar, Veronika Rupnik, Andreja Kovač, Didier Blanot, Stanislav Gobec, Danijel Kikelj, Lucija Peterlin Mašič

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 373 KB

english, 2009

38

Design and synthesis of new hydroxyethylamines as inhibitors of d-alanyl-d-lactate ligase (VanA) and d-alanyl-d-alanine ligase (DdlB)

Matej Sova, Gašper Čadež, Samo Turk, Vita Majce, Slovenko Polanc, Sarah Batson, Adrian J. Lloyd, David I. Roper, Colin W.G. Fishwick, Stanislav Gobec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 549 KB

english, 2009

39

Discovery of novel benzene 1,3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach

Andrej Perdih, Andreja Kovač, Gerhard Wolber, Didier Blanot, Stanislav Gobec, Tom Solmajer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.44 MB

english, 2009

40

Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall

Stanislav Gobec, Ivan Plantan, Janez Mravljak, Urban Švajger, Rosalind A. Wilson, Gurdyal S. Besra, Sousana L. Soares, Rui Appelberg, Danijel Kikelj

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 463 KB

english, 2007

41

A new approach towards peptidosulfonamides: synthesis of potential inhibitors of bacterial peptidoglycan biosynthesis enzymes MurD and MurE

Jan Humljan, Miha Kotnik, Audrey Boniface, Tomaž Šolmajer, Uroš Urleb, Didier Blanot, Stanislav Gobec

Journal:

Year:

2006

Language:

english

File:

PDF, 446 KB

english, 2006

42

Microwave-assisted synthesis of hydroxyethylamine dipeptide isosteres

Matej Sova, Andrej Babič, Slavko Pečar, Stanislav Gobec

Journal:

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

43

Synthesis of ethyl 3-(hydroxyphenoxy)benzyl butylphosphonates as potential antigen 85C inhibitors

Rok Frlan, Stanislav Gobec, Danijel Kikelj

Journal:

Year:

2007

Language:

english

File:

PDF, 304 KB

english, 2007

44

Synthesis of N-phthalimido β-aminoethanesulfonyl chlorides: the use of thionyl chloride for a simple and efficient synthesis of new peptidosulfonamide building blocks

Jan Humljan, Stanislav Gobec

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 133 KB

english, 2005

45

Epoxide opening with amino acids: improved synthesis of hydroxyethylamine dipeptide isosteres

Andrej Babič, Matej Sova, Stanislav Gobec, Slavko Pečar

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 94 KB

english, 2006

46

A general synthesis of ethyl 4-aminophenyl and ethyl 4-[amino(hydroxyimino)methyl]phenyl phosphonates

Stanislav Gobec, Katja Štrancar, Uroš Urleb

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 73 KB

english, 2002

47

Effect of selective and non-selectiveβ-blockers on body weight, insulin resistance and leptin concentration in chronic heart failure

Dragan Kovačić, Matej Marinšek, Lidija Gobec, Mitja Lainščak, Matej Podbregar

Journal:

Clinical Research in Cardiology

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

48

Modulation of tumour necrosis factor production with desmuramyldipeptide analogues

Saša Simčič, Branka Wraber, Marija Sollner, Uroš Urleb, Stanislav Gobec

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 448 KB

english, 2000

49

Virtual screening for potential inhibitors of bacterial MurC and MurD ligases

Tihomir Tomašić, Andreja Kovač, Gerhard Klebe, Didier Blanot, Stanislav Gobec, Danijel Kikelj, Lucija Peterlin Mašič

Journal:

Journal of Molecular Modeling

Year:

2012

Language:

english

File:

PDF, 802 KB

english, 2012

50

Cinnamic acid esters as potent inhibitors of fungal 17β-hydroxysteroid dehydrogenase––a model enzyme of the short-chain dehydrogenase/reductase superfamily

Stanislav Gobec, Matej Sova, Katja Kristan, Tea Lanišnik Rižner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004